1,458 research outputs found
Physical and Sexual Violence, Mental Health indicators, and treatment seeking among street-based population groups in Tegucigalpa, Honduras
To establish the prevalence of exposure to physical and sexual violence, mental health symptoms, and medical treatment-seeking behavior among three street-based subpopulation groups in Tegucigalpa, Honduras, and to assess the association between sociodemographic group, mental health indicators, and exposure to violence
Rheology of distorted nematic liquid crystals
We use lattice Boltzmann simulations of the Beris--Edwards formulation of
nematodynamics to probe the response of a nematic liquid crystal with
conflicting anchoring at the boundaries under shear and Poiseuille flow. The
geometry we focus on is that of the hybrid aligned nematic (HAN) cell, common
in devices. In the nematic phase, backflow effects resulting from the elastic
distortion in the director field render the velocity profile strongly
non-Newtonian and asymmetric. As the transition to the isotropic phase is
approached, these effects become progressively weaker. If the fluid is heated
just above the transition point, however, another asymmetry appears, in the
dynamics of shear band formation.Comment: 7 pages, 4 figures. Accepted for publication in Europhys. Let
Patterned silicon substrates: a common platform for room temperature GaN and ZnO polariton lasers
A new platform for fabricating polariton lasers operating at room temperature
is introduced: nitride-based distributed Bragg reflectors epitaxially grown on
patterned silicon substrates. The patterning allows for an enhanced strain
relaxation thereby enabling to stack a large number of crack-free AlN/AlGaN
pairs and achieve cavity quality factors of several thousands with a large
spatial homogeneity. GaN and ZnO active regions are epitaxially grown thereon
and the cavities are completed with top dielectric Bragg reflectors. The two
structures display strong-coupling and polariton lasing at room temperature and
constitute an intermediate step in the way towards integrated polariton
devices
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IL-27R signalling mediates early viral containment and impacts innate and adaptive immunity after chronic lymphocytic choriomeningitis virus infection
Chronic viral infections represent a major challenge to host's immune response and a unique network of immunological elements, including cytokines, are required for their containment. By using a model persistent infection with the natural murine pathogen lymphocytic choriomeningitis virus clone 13 (LCMV Cl13) we investigated the role of one such cytokine, interleukin 27 (IL-27), in the control of chronic infection. We found that IL-27R signalling promoted control of LCMV Cl13 as early as day 1 and 5 after infection and that il27p28 transcripts were rapidly elevated in multiple subsets of dendritic cells (DCs) and myeloid cells. In particular, plasmacytoid DCs (pDCs), the most potent type-1-interferon (IFN-I) producing cells, significantly increased il27p28 in a TLR7 dependent fashion. Notably, mice deficient in IL-27 specific receptor (R), WSX-1, exhibited a pleiotropy of innate and adaptive immune alterations after chronic LCMV infection, including compromised NK cell cytotoxicity and antibody responses. While, the majority of these immune alterations appeared cell-extrinsic, cell-intrinsic IL-27R was necessary to maintain early pDC numbers, which, alongside lower IFN-I transcription in CD11b+ DCs and myeloid cells, may explain the compromised IFN-I elevation that we observed early after LCMV Cl13 infection in IL-27R-deficient mice. Together these data highlight the critical role of IL-27 in enabling optimal anti-viral immunity early and late after infection with a systemic persistent virus and suggest that a previously unrecognized positive feedback-loop mediated by IL-27 in pDCs might be involved in this process
Comparison of 6LoWPAN and LPWAN for the Internet of Things
By 2020, 50 billion devices (things) are expected to be connected to the Internet to form the Internet of Things (IoT) world. In general, two main categories of networks are used in the IoT: short-range and long-range low-power networks. IPv6 over low-power wireless personal area networks (6LoWPAN) are considered to be a crucial network in short-range low-power networks where 6LoWPAN motes will account for the majority of short-range low-power things. Also, LoRaWAN and SigFox are two major networking landscapes and players in long-range, low-power networks or oftentimes called low-power wide area networks (LPWAN). This paper reviews and compares 6LoWPAN and LPWAN in terms of network architecture, protocol stack, applications and security. In general, LPWAN networks are more demanding in terms of node and link constraints than 6LoWPAN networks (e.g. very low payload size, very low data rate and very limited resources). Also, as yet, LPWAN networks do not have IPv6 addressing capabilities. Each network category has its unique characteristics and strengths and each category has its important role in the IoT world
STATISTICAL ANALYSIS OF THE EFFECTS OF MIXING POTATO VARIETIES ON LATE BLIGHT
A field study in two regions of Peru was conducted to determine how host-diversity effects on potato late blight varied geographically. Foliar disease severity was evaluated separately for the potato varieties in mixtures as well as in the single-variety plots. The TAUDPC (truncated area under the disease progress curve) and RMR (relative mixture response) for each site were analyzed separately using SAS mixed effects model procedures. While there was little difference between the sites in the 1997-1998 season, host-diversity effects were generally greater near Huancayo than near Cajamarca in the 1998-1999 season. Estimates of host-diversity effects from studies in Oregon and Ecuador were also compared with results for Peru. Host-diversity effects for reduced disease were generally greater for sites where we predicted lower levels of outside inoculum
Designing healthy communities: A walkability analysis of LEED-ND
AbstractPrevailing city design in many countries has created sedentary societies that depend on automobile use. Consequently, architects, urban designers, and land planners have developed new urban design theories, which have been incorporated into the Leadership in Energy and Environmental Design for Neighborhood Development (LEED-ND) certification system. The LEED-ND includes design elements that improve human well-being by facilitating walking and biking, a concept known as walkability. Despite these positive developments, relevant research findings from other fields of study have not been fully integrated into the LEED-ND. According to Zuniga-Teran (2015), relevant walkability research findings from multiple disciplines were organized into a walkability framework (WF) that organizes design elements related to physical activity into nine categories, namely, connectivity, land use, density, traffic safety, surveillance, parking, experience, greenspace, and community. In this study, we analyze walkability in the LEED-ND through the lens of the nine WF categories. Through quantitative and qualitative analyses, we identify gaps and strengths in the LEED-ND and propose potential enhancements to this certification system that reflects what is known about enhancing walkability more comprehensively through neighborhood design analysis. This work seeks to facilitate the translation of research into practice, which can ultimately lead to more active and healthier societies
Target Selection for the SDSS-IV APOGEE-2 Survey
APOGEE-2 is a high-resolution, near-infrared spectroscopic survey observing
roughly 300,000 stars across the entire sky. It is the successor to APOGEE and
is part of the Sloan Digital Sky Survey IV (SDSS-IV). APOGEE-2 is expanding
upon APOGEE's goals of addressing critical questions of stellar astrophysics,
stellar populations, and Galactic chemodynamical evolution using (1) an
enhanced set of target types and (2) a second spectrograph at Las Campanas
Observatory in Chile. APOGEE-2 is targeting red giant branch (RGB) and red
clump (RC) stars, RR Lyrae, low-mass dwarf stars, young stellar objects, and
numerous other Milky Way and Local Group sources across the entire sky from
both hemispheres. In this paper, we describe the APOGEE-2 observational design,
target selection catalogs and algorithms, and the targeting-related
documentation included in the SDSS data releases.Comment: 19 pages, 6 figures. Accepted to A
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